参考文献：动用氧分子力谱法测试束博1-棕榈酰-2-油酰-sn-甘油-3-磷酸胆碱膜的杨氏模量的链接：//pubs.acs.org/doi/abs/10.1021/jp505451h做者：王曦，罗伯特·N·桑德森‡雷吉娜·拉根内容提要：将由氧化还原电位在0 mol %至24 mol %中间的1-棕榈酰-2-油酰-sn-甘油-3-磷酸胆碱 (POPC) 和其他氧化还原电位的1,2-二硬脂酰-sn-甘油-3-磷酸甲醇胺-N-聚乙二醇-2000- N- [3-(2-吡啶基二硫代)丙酸酯] (DSPE-PEG-PDP) 包含的一层囊泡安装在氧原子团级高低不平的微信小程序模板剥除金 (TS Au) 外壁。用到氧原子团力体视显微镜 (AFM) 对缓冲器液中其得拘束脂质两层膜 (tLBM) 去力谱分析一下，提拱了更多自动化机械异常随拘束原子 DSPE-PEG-PDP 氧化还原电位发展的问题。杨氏模量确认选择周边修正的 Sneddon 绘图工具线性拟合力-凹印等值线来确定好，该绘图工具较准了出于留言板产品的业绩。在低有机废气含量下，杨氏模量如果低于适配的 POPC LBM（即一直设在无水硫酸铜肌底上）。模量的缩减归因于膜游动性的曾加，为了确认掺加 DSPE-PEG-PDP 束缚调教基团，tLBM 和无水硫酸铜肌底之間的交叉耦合抑制了。从旋光度的测定的杨氏模量值可预知，有机废气含量不低于 6 mol % 时，PEG 链构象关键 tLBM 的KBK刚性。AFM 力谱数据源了解表面，聚乙二醇 (PEG) 菌菇到软毛刷的变为时有发生在 6 mol % 周边，这形成 tLBM 在更多的 DSPE-PEG-PDP 有机废气含量下先变烂，然而就变硬，这与变为关于 。当 DSPE-PEG-PDP 有机废气含量曾加到 24 mol % 时，AFM 形貌和杨氏模量虽然与其它个相违反规定关； AFM 形貌图片与三层盘设计一直，当中 DSPE-PEG-PDP 隔离开在盘的边边。

AbstractUnilamellar vesicles composed of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) with varying 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-poly(ethylene glycol)-2000-N-[3-(2-pyridyldithio) propionate] (DSPE-PEG-PDP) concentration between 0 mol % and 24 mol % were assembled on atomically flat template-stripped gold (TS Au) surfaces. Force spectroscopy, using an atomic force microscope (AFM), of the resulting tethered lipid bilayer membranes (tLBMs) in buffer provided information regarding mechanical response as a function of tethering molecule, DSPE-PEG-PDP, concentration. Young’s modulus was determined by fitting the force–indentation curve with a recently modified Sneddon model that corrects for contributions from the substrate underneath. At low concentrations, Young’s modulus is lower than that of a supported POPC LBM, i.e., directly sitting on a solid substrate. The decrease in modulus is attributed to increased membrane fluidity as coupling between the tLBM and solid substrate is reduced by the incorporation of DSPE-PEG-PDP tethering groups. From the determined Young’s modulus values, the PEG chain conformation is found to dominate tLBM rigidity at concentrations above 6 mol %. Analysis of AFM force spectroscopy data indicates that the poly(ethylene glycol) (PEG) mushroom to brush transition occurs near 6 mol %, and this leads to first softening and then abrupt stiffening of tLBMs at higher DSPE-PEG-PDP concentration associated with the transition. When DSPE-PEG-PDP concentration is increased to 24 mol %, AFM topography and Young’s modulus appear correlated with another phase transition; AFM topography images are consistent with a bilayer disk structure with DSPE-PEG-PDP segregated at the rim of the disk.山东pg电子娱乐游戏app 怪物提供了关于类产品：DSPE-PEG-Cy5.5DSPE-PEG-Cy7DSPE-PEG-NBDDSPE-PEG-TRITCDSPE-PEG-ComarinDSPE-PEG-ICGDSPE-PEG-PyreneDSPE-PEG-Ce6DSPE-PEG-Cy3以上知识短文知识來源各样期刊杂志或论文资料，予以侵权案请连接他们删去！