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T7-PEG-PCL胶束载药系统的制备及表征
发布时间:2025-07-10     作者:kx   分享到:
文章:BMS-1166靶点递送增強乳腺炎癌抗体*图片链接://www.tandfonline.com/doi/full/10.2147/IJN.S497089#d1e381做者:于哲成,周泽亚&周瑜琪节选:方式方法将BMS-1166装封于T7-PEG-PCL胶束中。利用信息光散射测得粒度分布和zeta电势差。利用散射电子器材光学显微镜科学钻研颗料形貌。利用傅里叶更改红外光谱图、热重钻研和差示打印机扫描量热法对颗料去分析方法。利用高效率液质色谱判断药物剂量包封率、载药量和发出曲线美。以人甲状腺癌MDA-MB-231血受损神经元去血受损神经元致癌性测试。选取普鲁士蓝染色血受损神经元术和免疫神经细胞核荧光激光散斑科学钻研血受损神经元外表和外泌体中PD-L1的治理和改善现状。MDA-MB-231与Jurkat共提升科学钻研T血受损神经元滋养和凋亡现状。MethodsBMS-1166 was encapsulated in T7-PEG-PCL micelle. Particle size and zeta potential were determined by dynamic light scattering. Particle morphology was studied by transmission electron microscopy. The particles were characterized by Fourier transform infrared, thermogravimetric analysis, and differential scanning calorimetry. Drug encapsulation efficiency, loading degree, and release profile were examined by high-performance liquid chromatography. Human breast cancer MDA-MB-231 was used to test the cytotoxicity. Flow cytometry and immunofluorescence imaging were used to study the PD-L1 inhibition in cell surface and exosomes. MDA-MB-231 and Jurkat co-culture studied T-cell activation and apoptosis.

T7-PEG-PCL

昆明pg电子娱乐游戏app 生物体给予关联软件:DSPE-PEG-Antinucleosome mAb 2C5(二硬脂酰基磷脂酰工业乙醇胺-聚乙二醇-*靶向治疗蛋白质)DSPE-PEI-DextranmPEG-DOPEDSPE-PEG-YCAREPPTRTFAYWG(二硬脂酰基磷脂酰乙酸乙酯胺-聚乙二醇-*靶向药物淀粉酶)DSPE-PEG-COOHDSPE-PEG-FSHB(二硬脂酰基磷脂酰甲醇胺-聚乙二醇-子宫卵巢癌靶向治疗肽)DSPE-PEG-Mannose,DSPE-PEG-Man及以上短文项目来源地各刊物或学术论文,如果侵权案请连续我国删出!