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T7-PEG-PCL胶束载药系统的制备及表征
发布时间:2025-07-10     作者:kx   分享到:
论文:BMS-1166靶向疗法递送提高乳线癌抗体*连接://www.tandfonline.com/doi/full/10.2147/IJN.S497089#d1e381我们:于哲成,周泽亚&周瑜琪节选:方式方法将BMS-1166封装类型于T7-PEG-PCL胶束中。利用动态化光散射测得粒状直径和zeta电极电位。利用散发出电子为了满足电子时代发展的需求,光学显微镜科学调查探讨粒状形貌。利用傅里叶调整红外光谱图、热重具体分析和差示扫面量热法对粒状展开定量分析。利用高效、性价比最高液质色谱探测药物剂量包封率、载药量和放身材曲线。以人乳腺纤维癌MDA-MB-231神经元展开神经元毒素耐压试验。按照流式的神经元术和免疫检测荧光影像科学调查探讨神经元表层和外泌体中PD-L1的遏制状态。MDA-MB-231与Jurkat共培养计划科学调查探讨T神经元滋养和凋亡状态。MethodsBMS-1166 was encapsulated in T7-PEG-PCL micelle. Particle size and zeta potential were determined by dynamic light scattering. Particle morphology was studied by transmission electron microscopy. The particles were characterized by Fourier transform infrared, thermogravimetric analysis, and differential scanning calorimetry. Drug encapsulation efficiency, loading degree, and release profile were examined by high-performance liquid chromatography. Human breast cancer MDA-MB-231 was used to test the cytotoxicity. Flow cytometry and immunofluorescence imaging were used to study the PD-L1 inhibition in cell surface and exosomes. MDA-MB-231 and Jurkat co-culture studied T-cell activation and apoptosis.

T7-PEG-PCL

上海pg电子娱乐游戏app 生物体展示 有关软件:DSPE-PEG-Antinucleosome mAb 2C5(二硬脂酰基磷脂酰甲醇胺-聚乙二醇-*靶向疗法蛋清)DSPE-PEI-DextranmPEG-DOPEDSPE-PEG-YCAREPPTRTFAYWG(二硬脂酰基磷脂酰酒精胺-聚乙二醇-*靶向治疗蛋白质)DSPE-PEG-COOHDSPE-PEG-FSHB(二硬脂酰基磷脂酰工业乙醇胺-聚乙二醇-卵泡癌靶向疗法肽)DSPE-PEG-Mannose,DSPE-PEG-Man之内散文相关内容因素以及杂志或专著,烦请侵犯著作权请连系当我们误删!