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SH-PEG-COOH修饰金纳米棒的合成及多模态信号增强应用研究
发布时间:2025-07-15     作者:zyl   分享到:
文章:Surface Functionalized Gold Nanorods: Tracking and Observing Live Cell via Three Optical Signals 小说家:Qiu, Xiaozhong; Wang, Yaling; Cui, Yanyan; Sun, Zhipeng; Liu, Ru; Huang, Wenhua; Zhao, Feng; Zu, Yan; Yuan, Hui; Chang, Xueling; Gao, and Xueyun文献综述微信链接: Surface functionalized gold nanorods (GNRs) with three optical signals and the ability to track and observe live cells was investigated. The Cetyltrimethyl Ammonium Bromide (CTAB) was used as the shape-directing agent to develop GNRs with uniform size and aspect ratio. The as-synthesized GNRs can strongly enhance the Raman signal of the attached MGITC on the GNRs. Polyethylene glycol (SH-PEG-COOH) and SH-PEG-FITC were attached with GNRs through ligand exchange with CTAB. They can stabilize the GNRs, reduce the cytotoxicity and provide fluorescence signal. A cell-penetrating peptide was covalently conjugated with SH-PEG-COOH to assist the GNRs to enter living cell. After cultured with the MCF-7 cells, the surfaced functionalized Au nanorods can enter the MCF-7 cells and be tracking with enhanced MGITC Raman signal, FITC fluorescence, and Rayleigh scatter signal.

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科研了还具有3种光走势的外表面作用化金纳米技术棒(GNR)及其定位跟踪和分析活组织细胞的特性。采用16烷基三甲医院基溴化铵(CTAB)为形状图片大全指引剂,激发出厚度和丛横比不匀的GNR。合成视频的GNR能够 浓烈增进GNR上映照的MGITC的拉曼网络信号。聚乙二醇(SH-PEG-COOH)和SH-PEG-FITC在与CTAB的配体更换与GNR接。想一想可不可以相对稳定GNR,消减组织神经元核致毒并给予荧光电磁波。组织神经元核可穿透肽与SH-PEG-COOH共价构建,以让GNR进入到活组织神经元核。与MCF-7血细胞核一并养成后,外层官能化的Au纳米技术棒可以开启MCF-7血细胞核,混用加强的MGITC拉曼移动数据、FITC荧光和瑞利散射移动数据去监控。有关介绍:SH-PEG-RGDSH-PEG-EPOGala-PEG-SHSH-PEG-NTASH-PEG-DASH-PEG-SCMDBCO-PEG-SHSH-PEG-NH-MethoxyphenoneSH-PEG-SCSH-PEG-HZACA-PEG-SHSH-PEG-OHAC-PEG-SHAlKyne-PEG-SH上面文章知识知识来源于几大类杂志或专著,如无抄袭请找人们刪除!