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mPEG-EPO共聚AzPheEO制备及结构表征
发布时间:2025-07-16     作者:kx   分享到:
医学文献:聚乙二醇接枝光化学反应性聚乙二醇的合并与分析方法简答在防生物体污损应用领域这方面的研究分析链接转换://www.mdpi.com/2073-4360/15/1/184小说作家:马哈茂德·H·奥斯曼1,2奥西德,伊藤义弘1,2,3,*奥西德和秋元准节选:EO、AzPheEO和mPEG-EPO的共聚先要,将丙稀酸乙烷 (EO) 与 AzPheEO 和 mPEG-EPO 共聚(方案格式 1)。似乎,将 TBAB、AzPheEO 和 mPEG-EPO 在真空体下缺水处理 2 钟头内,那么暴露自己于缺水处理氢气中。将甲苯添加烧瓶中以融解 mPEG-EPO。马上又,将 EO 硫酸铜液体和 i-Bu 3 Al 添加居于冰浴中的烧瓶中。将硫酸铜液体在 25 °C 下闭光搅拌装置共聚 18 钟头内。将甲醇添加硫酸铜液体中,释压出掉容剂。将粗氧化物融解于甲苯中,并将硫酸铜液体用水量透析五天。那么将得到汇聚物冷却缺水处理,又称 AzPEGx [y],表中 x 和 y 各用代理 Mn 和 mPEG-EO 的装料比。得到 AzPEGx [y] 汇聚物主要包括了1 H-核磁共震 (NMR) 光谱介绍法 (JNM-ECZ400R, 400 MHz, JEOL, 日式悉尼) 在氯仿中对其使用定性介绍,并且主要包括了妇科凝胶构建色谱法 (GPC; JASCO, 日式悉尼) 对其使用定性介绍。该控制系统人员配备单台折射率率验测器 (RI-2032, JASCO, 日式悉尼) 和两条离子交换柱 (SB-803 HQ 和 SB804 HQ; Showa Denko, 日式悉尼),在有效 10 mM 溴化锂的二甲基甲酰胺 (DMF) 中对其使用介绍。

mPEG-EPO

 Copolymerization of EO, AzPheEO, and mPEG-EPOFirst, EO was copolymerized with AzPheEO and mPEG-EPO (Scheme 1). For this, TBAB, AzPheEO, and mPEG-EPO were dried under vacuum for 2 h, after which they were exposed to dry nitrogen. Toluene was added to the flask to dissolve mPEG-EPO. Subsequently, the EO solution and i-Bu3Al were added to the flask in an ice bath. The solution was stirred for copolymerization at 25 °C in the dark for 18 h. Methanol was added to the solution, and the solvent was removed under reduced pressure. The crude compound was dissolved in acetone, and the solution was dialyzed against water for three days. The resulting polymer was then freeze-dried and is referred to as AzPEGx [y], where x and y represent the Mn and feed ratio of mPEG-EO, respectively. The obtained AzPEGx [y] polymer was characterized via 1H-nuclear magnetic resonance (NMR) spectroscopy (JNM-ECZ400R, 400 MHz, JEOL, Tokyo, Japan) in chloroform, as well as via gel permeation chromatography (GPC; JASCO, Tokyo, Japan). The system was equipped with a refractive index detector (RI-2032, JASCO, Tokyo, Japan) and two columns (SB-803 HQ and SB804 HQ; Showa Denko, Tokyo, Japan) in dimethylformamide (DMF) containing 10 mM lithium bromide.绵阳pg电子娱乐游戏app 生物学供给相关的货品:DOPCDSPE-PEG-MannoseDSPE-PEG-RhodamineDOPE-PEG-SCDSPE(Sodium salt)-PEG-COOHDOPE-PEG-MalDSPE-PEG-多肽(各种各样的私人定制)DSPE-PEG-Ce6以下经典文章网站内容特征各种类型期刊论文或论文,要是有侵犯知识产权请保持在线留言大家删掉!