文献：Prostate cancer targeted magnetic resonance imaging nanoprobes based on polyethylene glycol polyethyleneimine and superparamagnetic iron oxide

小说作家：周建华，黄绿，王伟伟，庞俊，邹艳，帅心涛，高新技术文献综述跳转：//xueshu.baidu.com/usercenter/paper/show?paperid=c51dc88dae42acd9da7f55aeefd5bfbf&site=xueshu_se论文摘要：A water-soluble copolymer of polyethylene glycol grafted polyethyleneimine (mPEG-g-PEI) was obtained by grafting branched polyethyleneimine (hy PEI) onto monomethyl ether polyethylene glycol (mPEG-OH). Superparamagnetic iron oxide nanoparticles (SPIO) were encapsulated by ligand exchange, and then functionalized polyethylene glycol (mal PEG COOH) was combined with activated prostate stem cell antigen (PSCA) monoclonal single chain antibody to obtain a targeted magnetic resonance imaging nanoprobe for prostate cancer cells Research has shown that the particle size of polyethylene glycol grafted polyethyleneimine (mPEI-g-PEG-SPIO) loaded with superparamagnetic iron oxide nanoparticles is about 50nm, which can significantly improve the specific delivery efficiency to prostate cancer cells, thereby significantly reducing the T2 signal intensity of magnetic resonance imaging (MRI) of prostate cancer cells and enhancing the recognition efficiency of prostate cancer. It may become a new nano probe for early diagnosis of prostate cancer MRI or a visible nucleic acid delivery carrier in gene therapy

使用单甲基醚聚乙二醇(mPEG-OH)接枝支化聚乙稀亚胺(hy-PEI),得以水无水磷酸氢共 聚物聚乙二醇接枝聚乙稀亚胺(mPEG-g-PEI),依据配体变换的技术包装超顺带磁四钝化三铁奈米技术级技术激光束束(SPIO),再依据功能键化的聚乙二醇 (mal-PEG-COOH)与活性的前茅腺干组织抗原(PSCA)单克隆单链抵抗能力紧密联系,拿到前茅腺*组织靶点核磁共震显像奈米技术级技术电极.探析显示,装载超顺 带磁四钝化三铁奈米技术级技术激光束束的聚乙二醇接枝聚乙稀亚胺(mPEI-g-PEG-SPIO)的比表面积约为50nm,能同质性加快对前茅腺*组织的特男人输料高效应,从 而同质性地降底前茅腺*组织的核磁共震三维成像(MRI)T2的信号比强度,增进对前茅腺*的辨别高效应,有可以加入其中的前茅腺*MRI所以，金星由于这些原因原因新形奈米技术级技术电极一些染色体 治療中其中的MRI看得见的核酸输料质粒.想关引荐：PEI-PEG-SHPEI-PEG-cRGDPEI-PLGAPEI-PLAPEI-PCLPEI Hyaluronate (PEI-HA)PEI-DextranPEI-ChitosanmPEG-PCL-PEIX-PEI-Y 不低于文章內容內容源于当下杂志期刊或参考文献，如无侵犯知识产权请练习我删了！