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mPEG-SAA 的制备与纯化工艺
发布时间:2025-07-18     作者:kx   分享到:
资料:具有着群聚诱惑亮光的氧化物重现敏感脆弱整合物胶束使用于生物技术成相和*癌用量的递送图片链接://link.springer.com/article/10.1186/s12951-020-00761-9小说家:孙长振,吉禄,王俊,郝平,李春红,陆奇,林杨何斌钟志荣&那好节选:mPEG-SAA的合并将mPEG(0.2 g,0.1 mmol)和SAA(0.05 g,0.5 mmol)溶解于60 mL无水二氯丁烷中,的剧烈均匀搅拌器装置。冰浴下,将吡啶(0.4 mL)逐中滴加入分层物中。室内温度下均匀搅拌器装置48 h。在均匀搅拌器装置下,向反响指标工作体系里加入适量的乙酸,以中合指标工作体系中转化的盐。筛选去除放置自己,多效蒸发滤液,将粗品副产物放置自己于多冷乙醚中。去重复此纯化进行三次,拥有mPEG-SAA。

mPEG-SAA

Synthesis of mPEG-SAAThe mPEG (0.2 g, 0.1 mmol) and SAA (0.05 g, 0.5 mmol) were dissolved in 60 mL of anhydrous CH2Cl2 with strong stirring. Pyridine (0.4 mL) was added dropwise to the mixture on an ice bath. The mixture was stirred at room temperature for 48 h. An appropriate amount of acetic acid was added to the reaction system under stirring in order to neutralize salts produced in the system. The precipitate was removed by filtration, the filtrate was evaporated and the crude product was precipitated in a large volume of cold diethyl ether. This purification procedure was repeated several times to yield mPEG-SAA.武汉pg电子娱乐游戏app 生物工程出具各种相关品牌:DSPE-PEG-GE11(二硬脂酰基磷脂酰酒精胺-聚乙二醇-*神经细胞表面层植物生长成分EGFR靶向药物肽)DSPE-PEG-N3DSPE-PEG-RGD 二硬脂酰基磷脂酰工业乙醇胺-聚乙二醇-多肽DSPE-PEG-OX26 mAb(二硬脂酰基磷脂酰工业乙醇胺-聚乙二醇-*靶向药物淀粉酶)Angiopep-2-PEG-DSPE及以上的文章知识起源各种类型期刊杂志或论文参考文献,比如侵犯知识产权请联系起来各位删去!