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DSPE-PEG-TPP功能化MoS₂量子点的构建与表征
发布时间:2025-07-23     作者:zyl   分享到:
资料:The role of MoS2 QDs coated with DSPE-PEG-TPP in the protection of protein secondary structure of the brain tissues in an Alzheimer's disease model小说作家:Ohoud Abdulaziz Alamri a b, Safaa Qusti b, Maha Balgoon b, Abeer A. Ageeli c, F.A. Al-Marhaby d, Abeer M. Alosaimi e, Mohammed A. Jowhari f, Abdu Saeed g 论文连接: 论文摘要:In a recent groundbreaking study [13], a pioneering approach was employed utilizing MoS2 QDs coated with 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(poly-ethyleneglycol)-2000] (DPSE-PEG) linked with (3-carboxypropyl)triphenylphosphonium bromide (TPP). This innovative compound, recognized for its novel mitochondria-targeted properties, represents a potential therapeutic avenue for AD treatment [13]. The strategic DSPE-PEG-TPP coating layer serves as an essential interface, facilitating the attachment of MoS2 QDs to the mitochondria of microglia cells within brain tissues. Our present investigation builds upon this paradigm, delving into the intricate role of MoS2 coated with DSPE-PEG-TPP in safeguarding the protein secondary structure within brain tissues. Moreover, a comprehensive exploration of the impact of DSPE-PEG-TPP-MoS2 QDs treatment on a spectrum of biomarkers has been meticulously undertaken. Further elucidation of the methodology, detailed results, and an in-depth analysis can be found in subsequent sections, offering a comprehensive understanding of our study. This study sheds light on the role of MoS2 QD in the protection of the protein secondary structure of the brain tissues against AD etiology.

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采用了好几个种开设性的措施,采取涂有1,2-二硬脂酰基-sn-甘油-3-磷工业乙醇胺-N-[氨基(聚乙二醇)-2000](DPSE-PEG)的MoS2量子点,与(3-羧丙基)三苯基溴化鏻(TPP)进行连接。一种的创新化学物质而使有创意的线粒体靶点基本特征而受到了承认,表达了阿尔茨海默病的不确定制疗经由。发展战略定位的DSPE-PEG-TPP镀层是一种个极为重要的界面显示,驱动MoS2-QD黏附在神经组织安排内小胶质组织的线粒体上。.我近些年的深化分析建立起在这种范式的基础理论上,深化深化分析了涂有DSPE-PEG-TPP的MoS2在保护的神经细胞开展内淀粉酶质二次元设备构造多方面的僵化效果。最后,对DSPE-PEG-TPP-MoS2量子点方法对一编动物因素物的引响展开了新一轮的打磨。前边续章数中就能够进几步展现策略、图解结局和深入浅出定性分析,进而周全熟悉我们都的探析。本探析蕴含了MoS2-QD在保护区神经细胞安排蛋清质2级机构免遭AD病症影向管理方面的功用。对应网友推荐:mPEG-RGDmPEG-SS-CELmPEG-PLGA(30K)mPEG-PLGA(75:25)(5K)mPEG-DTA (ALC-0159) CAS No.: 1849616-42-7mPEG-DMG CAS No.: 160743-62-4mPEG-NBmPEG-PLA(15K)mPEG-PLGA(1K)mPEG-PLGA(10K)mPEG-PLGA(20K)mPEG-PEI(1K)上面的软文主要内容从何而来当下期刊论文或医学文献,假如侵犯商标权请连续我们公司删去!