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DSPE-PEG-TPP功能化MoS₂量子点的构建与表征
发布时间:2025-07-23     作者:zyl   分享到:
期刊论文:The role of MoS2 QDs coated with DSPE-PEG-TPP in the protection of protein secondary structure of the brain tissues in an Alzheimer's disease model著者:Ohoud Abdulaziz Alamri a b, Safaa Qusti b, Maha Balgoon b, Abeer A. Ageeli c, F.A. Al-Marhaby d, Abeer M. Alosaimi e, Mohammed A. Jowhari f, Abdu Saeed g 期刊论文联接: 前言:In a recent groundbreaking study [13], a pioneering approach was employed utilizing MoS2 QDs coated with 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(poly-ethyleneglycol)-2000] (DPSE-PEG) linked with (3-carboxypropyl)triphenylphosphonium bromide (TPP). This innovative compound, recognized for its novel mitochondria-targeted properties, represents a potential therapeutic avenue for AD treatment [13]. The strategic DSPE-PEG-TPP coating layer serves as an essential interface, facilitating the attachment of MoS2 QDs to the mitochondria of microglia cells within brain tissues. Our present investigation builds upon this paradigm, delving into the intricate role of MoS2 coated with DSPE-PEG-TPP in safeguarding the protein secondary structure within brain tissues. Moreover, a comprehensive exploration of the impact of DSPE-PEG-TPP-MoS2 QDs treatment on a spectrum of biomarkers has been meticulously undertaken. Further elucidation of the methodology, detailed results, and an in-depth analysis can be found in subsequent sections, offering a comprehensive understanding of our study. This study sheds light on the role of MoS2 QD in the protection of the protein secondary structure of the brain tissues against AD etiology.

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分为新一种再创性的方法步骤,根据涂有1,2-二硬脂酰基-sn-甘油-3-磷无水乙醇胺-N-[氨基(聚乙二醇)-2000](DPSE-PEG)的MoS2量子点,与(3-羧丙基)三苯基溴化鏻(TPP)衔接。这个不断创新有机物因为有高大上的线粒体靶向改善功能而感受到认可度,代表会了阿尔茨海默病的隐藏改善路经。发展计划性的DSPE-PEG-TPP表层有的是个关键性的程序界面,有利于MoS2-QD粘着在脑进行内小胶质血细胞的线粒体上。企业现在的探析树立在某一范式的基础性上,深入学习探析了涂有DSPE-PEG-TPP的MoS2在保护性脑安排内蛋白酶质一级设备构造领域的复杂性用途。虽然,对DSPE-PEG-TPP-MoS2量子点中药治疗对一全系列微生物标识物的关系实施了全方位的探讨。放前续第一章中能能更加骤阐发的方法、图解最后和更加深入分折,然后新一轮要了解各位的科学探索。本科学探索阐明了MoS2-QD在保护好脑集体蛋清质中级空间结构易受AD病症反应各方面的反应。对应引荐:mPEG-RGDmPEG-SS-CELmPEG-PLGA(30K)mPEG-PLGA(75:25)(5K)mPEG-DTA (ALC-0159) CAS No.: 1849616-42-7mPEG-DMG CAS No.: 160743-62-4mPEG-NBmPEG-PLA(15K)mPEG-PLGA(1K)mPEG-PLGA(10K)mPEG-PLGA(20K)mPEG-PEI(1K)往上软文方面来自各种期刊论文或专著,予以抄袭请关系公司删出!